SARMs
21 compounds
MK-777
MK-777 is a naming convention commonly used to refer to acetamoren, an orally active ghrelin receptor (GHSR1a) agonist and growth hormone secretagogue. In research settings, it is investigated for its ability to increase pulsatile growth hormone signaling and elevate downstream markers such as IGF-1, with secondary interest in sleep architecture, recovery, body composition endpoints, and catabolic state models.
MK-677
MK-677 (Ibutamoren) is a non-peptide small molecule researched as an agonist of the growth hormone secretagogue receptor (GHSR-1a), studied for its role in stimulating growth hormone (GH) release and downstream insulin-like growth factor 1 (IGF-1) signaling. Unlike peptide secretagogues, which require injection because the gut breaks them down, MK-677's non-peptide spiro-indoline structure allows oral dosing in research protocols, with reported bioavailability near 60%. It originated in the Merck research pipeline under the developmental codes MK-0677 and L-163,191. Reference data: PubChem CID 178024, CAS 159634-47-6 (free base) / 159752-10-0 (mesylate), molecular formula C27H36N4O5S, molar mass \~528.67 g/mol.
RAD-140
RAD-140, also known as Testolone, is a selective androgen receptor modulator (SARM) originally investigated as a treatment for hypogonadism, a potential male contraceptive aid, and more recently as a candidate treatment for hormone receptor-positive breast cancer. As a SARM, it is designed to bind androgen receptors with high selectivity, producing anabolic effects in muscle and bone tissue while minimizing androgenic activity in organs like the prostate. It carries a notably long half-life of approximately 60 hours, which is relevant to dosing interval discussions in research designs. RAD-140 is considered one of the more potent compounds in the SARM category and is associated with meaningful changes in body composition markers across preclinical and observational contexts.
RAD-140/YK-11
RAD-140/YK-11 is a two-compound research blend formulated for laboratory and analytical research applications. The formulation combines RAD-140, a selective androgen receptor modulator (SARM) studied for androgen receptor signaling, with YK-11, a steroidal SARM-like compound investigated in research for androgen receptor activity and myostatin-related signaling pathways. The blend is supplied as an aliquot solution in an advanced carrier system. RAD-140/YK-11 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
LGD-4033/YK-11
LGD-4033/YK-11 is a combined research formulation that pairs two commonly studied anabolic-signaling compounds in a single solution. It is typically investigated in controlled models where researchers evaluate androgen receptor-mediated signaling alongside pathways associated with myostatin-related regulation and muscle-cell differentiation. LGD-4033/YK-11 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
GW-501516 (Cardarine)
Cardarine (GW-501516) is a synthetic compound discussed as a PPARδ agonist, meaning it targets metabolic receptors involved in energy utilization and fuel partitioning rather than androgen receptors. It is often grouped with performance compounds, but it is not a SARM and does not work through the androgen receptor pathway. In research and athletic circles, it is primarily referenced for endurance support, fat metabolism signaling, and cardio performance enhancement.
MK-2866 (Ostarine)
Ostarine, also known as MK-2866, is a selective androgen receptor modulator (SARM) originally developed to investigate treatment for muscle wasting conditions and bone health support without the androgenic effects associated with traditional anabolic steroids. It selectively binds androgen receptors in muscle and bone tissue, promoting anabolic activity in those tissues while largely sparing androgenic effects elsewhere. Among SARMs, Ostarine is widely regarded as one of the milder and more well-tolerated options in the category, making it a common entry point in SARM research designs and a relevant variable in studies involving female models at lower exposure levels. It is also one of the few compounds in this category consistently associated with mood and joint health signals rather than the aggression or connective tissue stress observed with more androgenic compounds.
LGD-4033 (Ligandrol)
LGD-4033, also known as Ligandrol, is a synthetic selective androgen receptor modulator (SARM) originally developed to investigate treatment for muscle wasting, osteoporosis, and hormone-related conditions. It selectively binds androgen receptors in muscle and bone tissue with high affinity, producing significant anabolic signals without the full androgenic burden associated with traditional anabolic steroids. Among SARMs, LGD is widely regarded as one of the more effective bulking-oriented compounds in preclinical and observational research contexts, producing muscle volumization and fullness signals that are often compared in character to wet oral androgen effects due to water retention and tissue volumization observations. It is also noted as relatively joint-friendly and hair-safe compared to more androgenic compounds based on its selective receptor profile. LGD-4033 is not approved for human or veterinary use and is supplied strictly for laboratory research purposes.
YK-11 (Myostine)
YK-11 is a synthetic research compound commonly grouped with SARMs due to its interaction with androgen receptor signaling in experimental models. It is frequently discussed in research contexts for its potential to influence muscle growth related pathways through a combination of androgen receptor mediated activity and downstream effects on myostatin associated signaling. YK-11 is not approved for human or veterinary use and is supplied strictly for laboratory research purposes.
AC-262
AC-262 is an investigational selective androgen receptor modulator (SARM) studied in laboratory research for its androgen receptor-mediated signaling and potential tissue-selective characteristics in certain experimental models. In research settings, AC-262 is commonly evaluated for anabolic signaling endpoints in skeletal muscle and bone while monitoring androgenic activity across comparator tissues to assess relative selectivity. AC-262 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
RAD-150 (TLB-150)
RAD-150 (often referenced as TLB-150) is an investigational selective androgen receptor modulator (SARM) discussed in laboratory research for androgen receptor-mediated signaling and anabolic-pathway exploration. In research communities, RAD-150 is commonly described as a modified analog of RAD-140 intended to alter exposure characteristics. However, mechanistic and pharmacokinetic claims remain highly dependent on the specific material, formulation, experimental model, and study design. RAD-150 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
SR-9009 (Stenabolic)
SR-9009 (commonly referred to as Stenabolic) is an investigational research compound frequently studied in metabolic and circadian biology. Unlike selective androgen receptor modulators (SARMs), SR-9009 does not act through the androgen receptor. Instead, it is primarily investigated as a synthetic ligand for the REV-ERBα and REV-ERBβ nuclear receptors, which regulate circadian rhythms and downstream metabolic gene expression. SR-9009 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
LGD-3303
LGD-3303 is an investigational selective androgen receptor modulator (SARM) studied in laboratory settings for its androgen receptor (AR) activity in skeletal muscle- and bone-focused research models. Unlike traditional anabolic steroids, SARMs are designed to preferentially activate androgen receptor signaling in specific tissues, although observed tissue selectivity varies depending on the experimental model, dose, and duration of exposure. LGD-3303 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
S-4 (Andarine)
S-4, commonly referred to as Andarine, is an investigational selective androgen receptor modulator (SARM) studied in laboratory settings for its androgen receptor (AR) activity, particularly in skeletal muscle- and body-composition-focused research models. SARMs are designed to preferentially activate androgen receptor signaling in selected tissues compared with traditional anabolic steroids, although observed tissue selectivity depends on the experimental model, dose, and duration of exposure. S-4 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
S-23
S-23 is a synthetic nonsteroidal selective androgen receptor modulator (SARM) investigated for its high‑affinity binding to the androgen receptor and its ability to modulate anabolic pathways in a tissue‑selective manner. In research contexts, it is primarily explored for androgen receptor signaling, anabolic‑to‑androgenic selectivity, and comparative modeling versus classical anabolic steroids and other SARMs. Unlike steroidal androgens, S-23 is studied as a receptor‑level modulator designed to separate desired anabolic signaling from off‑target androgenic effects in non‑intended tissues.
SR-9011
SR-9011 is a synthetic small-molecule agonist of the nuclear receptor REV-ERBα (NR1D1), developed as a tool compound for probing circadian rhythm and metabolic gene regulation in laboratory models. In research contexts, it is primarily explored for modulation of circadian clock gene expression, mitochondrial oxidative metabolism, and energy-expenditure signaling, often alongside or in comparison to its close analog SR-9009. Unlike stimulatory agents that act via adrenergic or hormonal pathways, SR-9011 is studied as a transcription‑level modulator that influences metabolic programs by enhancing REV-ERBα repressor activity.
ACP-105
ACP-105 is an investigational selective androgen receptor modulator (SARM) studied in laboratory settings for androgen receptor (AR) activity, with emphasis on skeletal muscle- and body-composition-focused research models. As a nonsteroidal androgen receptor ligand, ACP-105 is investigated for its ability to activate androgen receptor-mediated transcriptional signaling in ways that may differ from traditional anabolic androgens depending on the experimental model, dose, and duration of exposure. ACP-105 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
GW-0742
GW-0742 is an investigational peroxisome proliferator-activated receptor delta (PPARδ) agonist studied in laboratory settings for its effects on metabolic gene expression, fatty-acid oxidation, and endurance-related physiology in controlled experimental models. Activation of PPARδ is commonly investigated for its ability to shift energy utilization toward oxidative metabolic pathways, particularly in skeletal muscle and liver, with downstream effects on lipid metabolism and exercise-performance-related endpoints. GW-0742 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
OTR-AC
OTR-AC is an investigational compound marketed within the broader SARM research category and is most commonly described as an Ostarine-related analog or variant, although naming conventions vary by supplier. In laboratory settings, OTR-AC is generally positioned as an androgen receptor (AR)-active research compound used to investigate how selective androgen receptor signaling may influence lean-mass retention, strength-related endpoints, and body-composition outcomes under controlled experimental conditions. Because "OTR-AC" is a trade-style designation rather than a universally standardized nonproprietary name, confirmation of compound identity—including analytical verification, purity assessment, and formulation characterization—is considered an important component of experimental design. OTR-AC is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
Capromorelin
Capromorelin is an investigational growth hormone secretagogue (GHS) class compound commonly described as a ghrelin receptor agonist used to study growth hormone (GH) axis modulation, appetite signaling, and downstream metabolic responses in controlled laboratory settings. In research contexts, it is typically positioned as a tool compound for probing how selective activation of the growth hormone secretagogue receptor (GHSR-1a) influences anabolic signaling, nutrient partitioning, and body composition proxies in vitro and in vivo models. Because “Capromorelin” is a well-known research and veterinary-development name but experimental lots can differ in salt form, excipients, and vehicle, identity confirmation (analytical verification, purity, and formulation) should be regarded as a core element of study design. Capromorelin is not approved for human use and products from Kimera Chems are supplied strictly for laboratory research applications only.
LGD-2226
LGD-2226 is an investigational nonsteroidal selective androgen receptor modulator (SARM) developed for laboratory research on androgen receptor (AR) signaling, with a focus on skeletal muscle and bone tissue selectivity relative to classical anabolic agents. In preclinical contexts, it is positioned as a tool compound to explore how selective AR activation influences lean mass, bone density, and anabolic versus androgenic signaling under controlled experimental conditions. Because “LGD-2226” is a research designation rather than a standardized INN, researchers should treat identity confirmation (analytical verification, purity, salt/formulation details, and vehicle) as a core part of experimental design. LGD-2226 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.