RAD-150 (TLB-150)
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RAD-150 (often referenced as TLB-150) is an investigational selective androgen receptor modulator (SARM) discussed in laboratory research for androgen receptor-mediated signaling and anabolic-pathway exploration. In research communities, RAD-150 is commonly described as a modified analog of RAD-140 intended to alter exposure characteristics. However, mechanistic and pharmacokinetic claims remain highly dependent on the specific material, formulation, experimental model, and study design. RAD-150 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes.
Available Formats
- Dry-fill capsules (10 mg, 60 count, 600 mg total)
- 10 mL aliquot vial (advanced carrier blend, 50 mg/mL, 500 mg total)
- 1 g powder
Mechanism of Action
RAD-150 is evaluated as a selective androgen receptor ligand in laboratory research. Common areas of mechanistic investigation include: Because the designation "RAD-150" is used across multiple product formats, meaningful interpretation generally requires verification of compound identity, purity, and the inclusion of structured comparator groups.
- Androgen receptor activation: Studied for its ability to bind androgen receptors and modulate androgen-responsive gene transcription under controlled experimental conditions
- Anabolic signaling: Investigated in skeletal-muscle models and commonly benchmarked against non-selective androgens and other SARMs
- Bone biology: Explored in studies evaluating bone turnover and bone-density endpoints where androgen signaling is an experimental variable
- Tissue selectivity: Assessed by comparing anabolic signaling with androgenic biomarkers in androgen-sensitive tissues
- Endocrine feedback: Longer-duration studies frequently monitor hypothalamic-pituitary-gonadal (HPG) axis biomarkers because androgen receptor agonism may influence endocrine feedback mechanisms
Areas of Investigation
RAD-150 is commonly studied in
- Skeletal-muscle hypertrophy and maintenance models
- Disuse-atrophy and muscle-wasting research
- Bone-density and skeletal-remodeling studies
- Androgen receptor selectivity across multiple tissue types
- Body-composition research with standardized dietary and activity variables
- Combination-study designs in which androgen signaling is evaluated alongside other experimental variables
Safety Profile
Reported observations are model- and exposure-dependent and may include
- Suppression-like findings involving hypothalamic-pituitary-gonadal (HPG) axis biomarkers and related endocrine measurements
- Alterations in lipid biomarkers, commonly monitored through HDL- and LDL-related endpoints during longer-duration studies
- Blood-pressure-related or sympathetic-activation findings in certain experimental models
- Sleep-disruption, irritability-like, or mood-variability findings in some exposure paradigms
- Elevations in hepatic-enzyme biomarkers reported in some oral-exposure studies, particularly when combined with other hepatically metabolized compounds
Interaction Notes
RAD-150 is often explored alongside interventions that overlap with androgenic and performance-related pathways.
For educational purposes only. Not for human consumption.