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SS-31

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Definition

SS-31 is a mitochondria-targeting peptide designed to protect and enhance mitochondrial function. It was developed to mitigate oxidative stress, improve energy production, and support cellular longevity, and it has been studied in research areas tied to anti-aging, cardiovascular health, and neuroprotection.

Available Formats

  • 10mg lyophilized peptide

Mechanism of Action

  • Mitochondrial protection and antioxidant effects through selective binding to cardiolipin, a key mitochondrial phospholipid, which stabilizes mitochondrial membranes and reduces oxidative damage.
  • Cellular longevity and energy optimization by supporting ATP production, improving mitochondrial efficiency, and helping mitigate mitochondrial dysfunction in high-energy-demand tissues like the heart, brain, and skeletal muscle.

Areas of Investigation

SS-31 is frequently studied for

  • Anti-aging and longevity support through improved mitochondrial resilience, helping slow age-related cellular decline and supporting tissue regeneration signals.
  • Cardiovascular health support through protection of cardiac tissue and reductions in ischemia-reperfusion injury signals, with research interest in improving heart function in models relevant to heart failure and myocardial infarction.
  • Neuroprotection and cognitive support through potential reductions in neurodegeneration signals, with research interest in models relevant to Alzheimer’s, Parkinson’s, and other neurological disorders.

Safety Profile

  • No major systemic adverse events reported in controlled preclinical testing

Interaction Notes

Researchers commonly explore SS-31 alongside other compounds depending on the study focus

  • Anti-aging synergy: Crystagen, Epithalon, GHK-Cu (including blends like GLOW or KLOW), Humanin, Methylene Blue, MOTS-c, NAD+, SS-31
  • Mitochondrial / energy-support models: MOTS-c, 5-Amino-1MQ, NAD+, Methylene Blue
  • Neuroprotective pathways: Methylene Blue, Cerebroprotein Hydrolysate (Cerebrolysin), NAD+, Dihexa, MOTS-c, Semax, Selank, FGL, DNSP-11, Humanin
Disclaimer

For educational purposes only. Not for human consumption.