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Peptides

PT-141

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Definition

PT-141 (Bremelanotide) is a melanocortin receptor agonist studied for its effects on libido, arousal pathways, sexual function, and CNS signaling. Unlike PDE5 inhibitors that work on blood flow, PT-141 directly targets melanocortin receptors in the brain, making it a unique research tool in behavioral and neuroendocrine fields.

Available Formats

  • 10mg lyophilized peptide

Mechanism of Action

PT-141 stimulates MC3R and MC4R melanocortin receptors, which are associated with: It does not act on the vascular system, setting it apart from ED medications.

  • Arousal and libido pathways
  • Sexual behavior signaling in animal models
  • Mood and appetite modulation
  • Neurotypical CNS responses

Areas of Investigation

PT-141 is researched for

  • Improved sexual function outcomes discussed in erectile dysfunction (ED) research in men and hypoactive sexual desire disorder (HSDD) research in women.
  • Enhanced libido and arousal signals in individuals with low sexual desire.
  • Non-hormonal therapeutic profile that works independently of hormones like testosterone or estrogen.

Safety Profile

  • PT-141 is generally described as well tolerated when used at recommended doses within research settings. Commonly reported side effects in research settings include nausea, headache, and flushing. These effects are typically mild and transient.
Disclaimer

For educational purposes only. Not for human consumption.