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Peptides

LL-37

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Definition

LL-37 is a cathelicidin antimicrobial peptide involved in immune defense, wound healing, and inflammation regulation. It is naturally produced by epithelial cells and immune cells, where it acts as a broad spectrum protective signal against bacteria, viruses, and fungi.

Available Formats

  • 5mg lyophilized peptide

Mechanism of Action

  • Antimicrobial activity: Helps disrupt pathogen membranes, reducing the ability of microbes to persist and spread.
  • Immune modulation: Tunes immune cell activity to support innate immunity while helping limit excess inflammatory signaling.
  • Wound healing support: Promotes tissue repair signals, including collagen related processes and improved skin recovery.

Areas of Investigation

LL-37 is commonly studied for

  • Infection defense: Supports immune function and resilience against infections, especially when immune defenses are compromised.
  • Skin health and wound healing: Commonly discussed for wound care, burn recovery, and chronic skin issues such as eczema and psoriasis.
  • Chronic inflammation support: May help regulate immune responses in inflammatory and autoimmune contexts by improving immune balance.

Safety Profile

LL-37 is generally well tolerated in research settings, particularly when used topically. Potential issues include

  • Mild skin irritation or localized allergic type reactions
  • Immune overstimulation risk in people with autoimmune disorders, so conservative use and careful monitoring are commonly emphasized
Disclaimer

For educational purposes only. Not for human consumption.