Fragment 176-191
Shop Fragment 176-191 on KimeraChems · code GUIDE (10% off)Definition
HGH Frag 176-191 is a modified peptide fragment derived from the last 15 amino acids of the full human growth hormone (HGH) sequence. It is designed to selectively study the fat-metabolism effects of GH without activating IGF-1–related growth pathways.
Available Formats
- 5mg lyophilized peptide
Mechanism of Action
HGH Frag 176-191 interacts with metabolic signaling pathways involved in lipolysis and fat oxidation. Research suggests it may: This selective activity makes it a common tool in metabolic-focused research.
- Increase fat breakdown in adipose tissue
- Reduce lipogenesis (new fat storage)
- Enhance fatty-acid availability for energy
- Influence energy-balance pathways without elevating IGF-1
- Act independently from the growth-promoting actions of full GH
Areas of Investigation
HGH Frag 176-191 is commonly studied for
- Fat-loss and adipose-tissue metabolism
- Energy-expenditure regulation
- Lipolytic pathway activation
- Anti-lipogenic signaling
- Potential roles in obesity-related models
- Glucose-handling stability compared to full GH
Safety Profile
Reported findings include: Overall, studies show a favorable profile compared to full GH due to its selective action.
- Mild injection-site redness
- Temporary fatigue
- Increased hunger in some models
- Occasional lethargy
- No IGF-1–related systemic effects
Interaction Notes
Commonly studied with: No harmful interactions have been reported in controlled preclinical models.
- GH secretagogues in metabolic-synergy models
- Lipolytic-pathway activators
- Peptides explored for weight-regulation research
For educational purposes only. Not for human consumption.