Aminos
5-Amino-1MQ
Shop 5-Amino-1MQ on KimeraChems · code GUIDE (10% off)Definition
5-Amino-1MQ is a synthetic small molecule designed to inhibit nicotinamide N-methyltransferase (NNMT), an enzyme implicated in fat storage and metabolic regulation. In research discussions, NNMT activity is emphasized in liver and adipose tissue models where higher expression is associated with increased fat accumulation and reduced metabolic efficiency
Available Formats
- Dry-fill capsules
- 20mL aliquot vial (50mg/mL)
- 5 grams powder
Mechanism of Action
Research indicates 5-Amino-1MQ may: These mechanisms make it of interest in metabolic, mitochondrial, and energy-regulation research.
- Inhibit NNMT activity, shifting metabolism away from fat storage and toward greater fat oxidation
- Improve metabolic efficiency by supporting higher energy expenditure and reduced fat accumulation signals
- Support mitochondrial function and cellular energy output in metabolically stressed models
- Reduce oxidative stress related markers downstream of improved mitochondrial performance
Areas of Investigation
5-Amino-1MQ is frequently explored in
- Metabolic rate and energy-balance models
- Mitochondrial function and NAD+ pathway research
- Obesity-related mechanistic studies
- Adipocyte biology and lipolysis pathways
- Exercise-performance and energy-output models
- NNMT inhibition research
Safety Profile
Documented findings include: Effects depend heavily on dosing and experimental conditions.
- Headache or pressure sensation
- Mild nausea
- Increased heart rate in certain models
- Temporary irritability
- Reduced appetite
Interaction Notes
Common research synergies include: Caution is advised when combined with
- Mitochondrial agents: MOTS-c, SS-31
- NAD+ pathway compounds: NMN, NR
- Metabolic modulators: Tirzepatide, AOD-9604, Fragment 176-191
- Energy-output agents: Methylene Blue, Creatine
- Strong stimulants
- Compounds increasing sympathetic activity
Disclaimer
For educational purposes only. Not for human consumption.